WebJun 15, 2002 · Two key events occur during the differentiation of IFN-gamma-secreting Th1 cells: up-regulation of IL-12Rbeta2 and IL-12-driven up-regulation of IL-18Ralpha. We previously demonstrated that IL-12-driven up-regulation of IL-18Ralpha expression is severely impaired in IFN-gamma(-/-) mice. However, it … WebWarning Our Product Finder has been designed to allow you to quickly identify the required product(s) for you; to offer an optimal experience, the saving of cookies ...
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