Phosphopyruvate hydratase, usually known as enolase, is a metalloenzyme (EC 4.2.1.11) that catalyses the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), the ninth and penultimate step of glycolysis. The chemical reaction is: 2-phospho-D-glycerate See more In humans there are three subunits of enolase, α, β, and γ, each encoded by a separate gene that can combine to form five different isoenzymes: αα, αβ, αγ, ββ, and γγ. Three of these isoenzymes (all homodimers) are … See more Using isotopic probes, the overall mechanism for converting 2-PG to PEP is proposed to be an E1cB elimination reaction involving … See more Small-molecule inhibitors of enolase have been synthesized as chemical probes (substrate-analogues) of the catalytic mechanism of the … See more • Enolase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) See more Enolase is a member of the large enolase superfamily. It has a molecular weight of 82,000-100,000 Daltons depending on the isoform. In human alpha enolase, the two subunits are antiparallel in orientation so that Glu of one subunit forms an ionic bond with See more In recent medical experiments, enolase concentrations have been sampled in an attempt to diagnose certain conditions and their severity. For example, higher concentrations of … See more • Holt A, Wold F (December 1961). "The isolation and characterization of rabbit muscle enolase". The Journal of Biological Chemistry. 236 (12): 3227–3231. doi:10.1016/S0021-9258(18)94000-7. PMID 13908561. • Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), … See more WebDeficiency of phosphopyruvate hydratase (124618001); Deficiency of 2-phosphoglycerate dehydratase (124618001); Deficiency of enolase (124618001) Definition. A rare, …
Fumarate Hydratase - an overview ScienceDirect Topics
WebPhosphopyruvate Hydratase / analysis Phosphopyruvate Hydratase / genetics Phosphopyruvate Hydratase / metabolism* Viscera / enzymology* Substances Amino … WebJun 13, 2005 · Generic Name Phosphoenolpyruvate DrugBank Accession Number DB01819 Background Not Available Type Small Molecule Groups Experimental Structure Similar Structures Weight Average: 168.042 Monoisotopic: 167.982374404 Chemical Formula C 3 H 5 O 6 P Synonyms Not Available Pharmacology Indication Not Available black panther wakanda forever hindi
phosphopyruvate hydratase complex SGD
WebChildren of phosphopyruvate hydratase activity (GO:0004634) EC 4.2.1.11 MetaCyc 2PGADEHYDRAT-RXN Reactome R-HSA-71660 R-HSA-70494 RHEA 10164 Cite this data• … WebPhosphopyruvate Hydratase / analysis Phosphopyruvate Hydratase / genetics Phosphopyruvate Hydratase / metabolism* Viscera / enzymology* Substances Amino Acids Isoenzymes Phosphopyruvate Hydratase ... Web神经元特异性烯醇化酶(英語: neuron specific enolase ,缩写NSE),也称为烯醇化酶2(enolase 2,ENO2)、γ-烯醇化酶(Gamma-enolase)是人类基因组中编码的三种烯醇化酶(也称做“磷酸烯醇式丙酮酸水合酶”, phosphopyruvate hydratase)之一,是小细胞肺癌和嗜铬细胞瘤的肿瘤标志物。 black panther wakanda forever hbo max