P-stathmin
![3925 - Gene ResultSTMN1 stathmin 1 [ (human)] - National Center …](https://ts2.mm.bing.net/th?q=3925 - Gene ResultSTMN1 stathmin 1 [ (human)] - National Center …)
Stathmin is a ubiquitous phosphorylated protein which makes it act as an intracellular relay for diverse regulatory pathways, functioning through a variety of second messengers. Its phosphorylation and gene expression are regulated throughout development [11] and in response to extracellular … See more Stathmin, also known as metablastin and oncoprotein 18 is a protein that in humans is encoded by the STMN1 gene. Stathmin is a highly conserved 17 kDa protein that is crucial for the regulation of the cell See more Stathmin, and the related proteins SCG10 and XB3, contain a N-terminal domain (XB3 contains an additional N-terminal hydrophobic region), … See more Stathmin interacts with two molecules of dimeric α,β-tubulin to form a tight ternary complex called the T2S complex. One mole of stathmin binds to two moles of tubulin dimers through the stathmin-like domain (SLD). When stathmin sequesters tubulin into the T2S … See more Mice without stathmin have deficiency in innate and learned fear. Stathmin−/− females do not assess threats well, leading to lack of … See more The function of Stathmin is to regulate the cytoskeleton of the cell. The cytoskeleton is made up of long hollow cylinders named microtubules. These microtubules are made up of alpha and beta tubulin heterodimers. The changes in cytoskeleton are … See more Stathmin's role in regulation of the cell cycle causes it to be an oncoprotein named oncoprotein 18 (op18). Stathmin (aka op18) can cause uncontrolled cell proliferation when mutated and not functioning properly. If stathmin is unable to bind to tubulin, it … See more • Sobel A (August 1991). "Stathmin: a relay phosphoprotein for multiple signal transduction?". Trends in Biochemical Sciences. 16 (8): … See more WebOp18/stathmin is a 17-kDa protein that has been recently revealed to bind tubulin and destabilize microtubules ( 19 ) and is negatively regulated by phosphorylation by a variety …
P-stathmin
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WebSep 8, 2015 · Stathmin and phospho-stathmin protein signature is associated with survival outcomes of breast cancer patients Oncotarget . 2015 Sep ... In conclusion, the STMN1 … WebFeb 22, 2010 · Stathmin, a microtubule-destabilizing protein, is dysregulated in spinal muscular atrophy† Human Molecular Genetics Oxford Academic Abstract. Spinal muscular atrophy (SMA), a motor neuron degeneration disorder, is caused by either mutations or deletions of survival motor neuron 1 (SMN1) gene
WebThe protein and mRNA expression of β-tubulin and MAP-1B was consistent with that of p-stathmin; it reached a peak on the 7th day, and then decreased in the rat hippocampus, … Web您好！欢迎来到炼石商城 请登录 注册 我的订单; 我的炼石
WebMay 1, 2009 · We have recently reported that stathmin, a microtubule regulatory protein, was expressed by human endometrial stroma, glandular, and vascular endothelium ( 12 ). Stathmin is a cytosolic phosphoprotein that contains four serine phosphorylation sites (Ser-16, -25, -38, and -63) at its N terminus ( 13 ). WebStathmin 1 is a microtubule-regulating protein that has an important role in the assembly and disassembly of the mitotic spindle . At the molecular level, Stathmin 1 depolymerizes microtubules by either sequestering free tubulin dimers or directly inducing microtubule-catastrophe . As mentioned before, Stathmin 1 is encoded by the human STMN1 ...
WebMar 6, 2024 · Dizziness or headache . Upset stomach or throwing up. Dry mouth. Trouble sleeping. These are not all of the side effects that may occur. If you have questions about …
WebMay 30, 2024 · Stathmin 1 expression is related to tumor size, category and lymph node status. Stathmin 1 expression correlates with PD-L1, TIM3, VISTA, B7-H3, B7-H4, LAG-3 and p-STAT3 expression in HNSCC. P-Stathmin 1 S38 expression correlates with PD-L1, VISTA, B7-H4, LAG-3 and p-STAT3 in HNSCC. honkai impact redeem code seaWebFeb 19, 2024 · High stathmin expression was associated with high histological grade in both cohorts (p ≤ 0.002), tumour diameter > 20 mm in cohort 1 (p = 0.018), and ER (estrogen … honkai impact new codesWebMar 26, 2024 · Stathmin-2 (encoded by STMN2 ), has recently been reported as a potential contributor to the pathogenesis of ALS ( Klim et al., 2024; Melamed et al., 2024 ). STMN2, … honkai impact project arkWebJan 17, 2024 · Non-small cell lung cancer (NSCLC) is among the leading causes of human mortality. One reason for high rates of NSCLC mortality is that drug resistance is a major problem for both conventional chemotherapies and less-toxic targeted therapies. Thus, novel mechanistic insights into disease pathogenesis may benefit the development of … honkai impact redeem code augustWeb靶向于her2的sirna表达载体在人乳腺癌细胞skbr3中的表达. 内容摘要：作者：鲍炜 张立红 付海京 贾林涛 张勇 刘家云 任新玲 温伟红 孟艳玲 王成济 杨安钢 作者：鲍炜 张立红 付海京 贾林涛 张勇 刘家云 任新玲 温伟红 孟艳玲 王成济 杨安钢 目的：探讨针对her2分子的rna干涉对 honkai impact ps4WebJan 13, 2024 · The protein expression of p-stathmin (Ser16, Ser25, Ser38, and Ser63) in the hippocampus of the control group and SPS groups was detected by Western blotting. A single band was observed at 19 kDa. The results showed that the p-stathmin (Ser25) and p-stathmin (Ser38) proteins were expressed in the hippocampus of the normal rats. honkai impact seven thunders of retributionWebSep 23, 2024 · A reduction in p-stathmin from the combination treatment destabilized microtubule assembly by tubulin depolymerization. The drug combination treatment in mice with human ACC xenografts resulted in a significantly lower tumor burden than those treated with single-agents and vehicle control groups. Conclusions honkai impact scythe