Otub2 t cell
WebThe vector of anti-OTUB2 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target Mouse OTUB2. The T cells are genetically modified … WebOct 25, 2024 · In the context of cancer, OTUB2 has been shown to promote non-small cell lung cancer initiation and progression by stabilizing U2 small nuclear ribonucleoprotein auxiliary factor 2 (Li et al., 2024 ). In addition, OTUB2 promotes breast cancer metastasis by stabilizing Yes-associated protein/WW domain-containing TFs ( Zhang et al., 2024 ).
Otub2 t cell
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WebMar 29, 2024 · OTUB2 is a novel promoter of viability and insulin secretion in human beta cells. OTUB2 acts through the inhibition of NF-kappaB signalling. Findings suggest that … WebRabbit polyclonal to OTUB2 Suitable for: WB Reacts with: Human Isotype: IgG You may also be interested in Protein Recombinant Human OTUB2 protein (ab106896) Secondary Goat Anti-Rabbit IgG H&L (HRP) (ab205718) Primary …
WebOct 1, 2024 · (G) Methylation frequencies at the OTUB2 locus in KYSE30 and KYSE140 cells treated with DMSO or 5-aza (10 mM) for 96 h. Eight colonies from each group were sequenced to calculate the methylation ... WebMar 2, 2024 · OTUB2 is involved in the deubiquitination of many key proteins in different cell signaling pathways, and the effect of OTUB2 on human health or disease is not clear. OTUB2 is likely to cause cancer and other malignant diseases while maintaining normal …
WebOTUB2. CELL LINE. Human cell lines. GENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as … WebSep 27, 2024 · Otubain 2 (OTUB2), a deubiquitinating enzyme, overexpression is considered to predict poor outcome in various cancers. However, the function and …
WebMar 2, 2024 · OTUB2 is involved in the deubiquitination of many key proteins in different cell signaling pathways, and the effect of OTUB2 on human health or disease is not clear. OTUB2 is likely to cause ...
WebJan 1, 2024 · In NSCLC cell lines, OTUB2 promoted cell growth, colony formation, migration, and invasive activities. Mechanistic investigations showed that OTUB2 stimulated the Warburg effect and induced the activation of the serine/threonine kinase/mechanistic target of rapamycin kinase (AKT/mTOR) pathway in different NSCLC cells. fresh produce group nz ltdWebFeb 20, 2014 · OTUB2-depleted cells exhibited faster dissolution of conjugated ubiquitin foci post-NCS treatment (Figure 3G), suggesting that DSB repair may be quicker in OTUB2-depleted cells than in control … fathead toysWebJan 3, 2024 · These results suggest that OTUB2 promotes cancer stem cell traits. OTUB2 barely/or lowly expressed in normal breast tissue or breast epithelial cells but strongly expressed in metastatic breast cancer cells ( Figures 1 B, 1C, S1 C, and S1D). To confirm a role of OTUB2 in cancer metastasis, we knocked out OTUB2 in the highly bone … fresh produce innovationWeb首页; 代理品牌. 产品类型; 品牌介绍; 定制/代测; 欣博盛品牌. 产品类型; 奖学金活动; 代测服务; 客户评鉴; 文献引用; 新闻资讯 fresh produce imagesWebOct 20, 2024 · Where indicated, cells were treated with 10 μM MG-132 for 4 h before being harvested. (B) OTUB2 increases steady state Gli2 protein levels. The stable cell line T-Rex-U2OS-Flag-DUBX cells were cultured in the absence or presence of different dosage of doxycycline (Dox) for 48 h. The cell lysates were immunoblotted with the indicated … fathead toys r usWebOTUB2 Introduction The Anti-OTUB2 (CB-P62) h (scFv-CD28TM-CD79β) CBCR (CAR-B) vector is composed of an anti-OTUB2 antibody-based binding domain, which is fused with the CD79β signaling domain, a component of the B cell receptor (BCR) complex that is responsible for activation. fathead tractorshttp://www.neobioscience.com/prod_view.aspx?TypeId=409&Id=2342024&FId=t3:409:3 fresh produce for sale online