Mouse hif1a
Nettet13. apr. 2024 · Indeed, in the developing mouse retina, Hypoxia-inducible factor-alpha (coded by Hif1a) stabilisation by the propyl isomerase inhibitor Roxadustat 45 upregulates Tnfsf9 expression in rod ... NettetRecognizes human and mouse HIF-1 alpha/HIF1A in direct ELISAs. Source Monoclonal Mouse IgG 1 Clone # 241812 Purification Protein A or G purified from hybridoma …
Mouse hif1a
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Nettet3. jun. 2015 · HIF-1α is an oxygen-regulated protein that functions as part of a heterodimeric complex, which it forms with HIF-1β in the nucleus. This complex binds to DNA at specific promoter or enhancer sites [hypoxia response elements (HREs)], resulting in transcriptional regulation of more than 100 gene products ( 27, 28 ). NettetHIF-1α is an intracellular oxygen sensor and plays a crucial role in regulating hepatic glucose and lipid metabolism in normal and pathological conditions ( 25 ). Increased liver HIF-1α promotes liver damage, steatosis, and inflammation in a rodent model of alcoholic steatohepatitis ( 26 ).
NettetPrimePCR™ Template for Probe Assay: Hif1a, Mouse Reaction: 200 x 20 µl reactions Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay. List Price: $215.00 Your Price: Log In Quantity: Add to Cart [ Add to ... NettetOur analysis of mice with Hif1aCKO in ISL1-expressing cells has revealed a key role for HIF-1α in sympathetic innervation of the heart and development of sympathetic ganglia. …
NettetMouse HIF-1 alpha ELISA Kit is a single-wash 90-min SimpleStep ELISA® for the quantitative measurement of Mouse HIF-1 alpha in Cell Lysate samples. Mouse HIF-1 … Nettet7. jan. 2012 · Overexpression of the oxygen-responsive transcription factor hypoxia-inducible factor 1α (HIF-1α) correlates with poor prognosis in breast cancer patients. The mouse mammary tumor virus polyoma virus middle T (MMTV-PyMT) mouse is a widely utilized preclinical mouse model that resembles human luminal breast cancer and is …
NettetThe hypoxia-inducible transcription factor 1 alpha (HIF-1 alpha ) is the regulated member of the transcription factor heterodimer HIF-1. HIF-1 binds to hypoxia-response elements …
Nettet12. apr. 2024 · Also, the miR-142-3p overexpression upregulated the mRNA of HIF1A, VEGFA, and GGT1. In conclusion, miR-142-3p functions as an oncogene in RCC, ... Female nude mice, ... snack bar items that sellNettetSpecificity of Human/Mouse HIF-1 alpha DuoSet IC ELISA is shown by Western Blot. Lysates prepared from NIH-3T3 mouse embryonic fibroblast cells, untreated or treated with 150 µM of CoCl 2, were incubated in wells coated with Human/Mouse Total HIF-1 alpha Capture Antibody.Unbound material was removed by washing, and bound … rmo limited stallingboroughNettet2 dager siden · Interestingly, Gm15283 also is the antisense transcript of mouse HIF1A but does not code for any proteins (Supplementary Fig. 14C), indicating Gm15283 is the equivalent gene of HIF1A-As2 (Here, we ... snack bar orchidea luganoNettetDescription Mouse monoclonal [mgc3] to HIF-1 alpha Host species Mouse Specificity This antibody does not cross-react with ARNT or the related HIF-2-alpha. Tested applications Suitable for: Flow Cyt, WB, IHC-P more details Species reactivity Reacts with: Human Predicted to work with: Mouse, Cow, Pig, Non human primates Immunogen rmo mechanical and instrumentationNettetInteracts with the ARNT; forms a heterodimer that binds core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters … snackbar oudeschootNettet产品描述. The ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of samples in serum, Plasma , Urine ,tissue homogenates and Cell culture supernates and Other biological fluids. 储存条件. Store unopened kit at 2-8 °C for1 week. snack bar names ideasNettet5. jan. 2024 · HIF-1α Antibody (H1α 67) is an IgG2b κ mouse monoclonal HIF-1α antibody suitable for the detection of HIF-1α of mouse, rat and human origin by WB, IP, IF and IHC (P). HIF-1α Antibody (H1α 67) is available as both conjugated and non-conjugated anti-HIF-1α antibody forms. Cell growth and viability is compromised by oxygen deprivation … rmo marketwatch