WebMay 9, 2005 · FISH,RT-PCR, and sequence analyses revealed an EWSR1–ATF1 fusion gene that has previously been reported in clear cell sarcoma (CCS), a soft tissue sarcoma that is morphologically and clinically distinct from AFH. This study thus has demonstrated that the EWSR1–ATF1 chimera represents a fusion gene that can be associated with … WebWe performed next-generation sequencing-based anchored multiplex polymerase chain reaction (Archer® FusionPlex® sarcoma assay), …
EWSR1-ATF1 Fusion - My Cancer Genome
WebUnlike melanoma, clear cell sarcoma harbors either a t(12;22)(q13;q12) recurrent translocation, resulting in an EWSR1/ATF1 chimeric gene, or less commonly a t(2;22)(q34;q12) translocation fusing EWSR1 and CREB1. Few studies have examined the prevalence of all chimeric types and variants to assess the usage of ancillary genetic … WebFeb 10, 2024 · Primary pulmonary myxoid sarcoma (PPMS) is an extremely rare lung sarcoma that is characterized in most cases by recurrent balanced chromosomal translocation t(2;22)(q33;q12) leading to the oncogenic fusion gene EWSR1-CREB1. We report a case of PPMS with molecular confirmation using fluorescence in situ … ganga international school new delhi
Malignant Peritoneal Mesothelioma With EWSR1-ATF1 …
WebDec 1, 2005 · The EWS-FLI1 fusion transcript was found to be present in 8/8 (100%) of the Ewing’s sarcoma cases, while the fusion transcript was not identified in the other … WebApr 27, 2024 · The relationship between cellular histogenesis and molecular phenotypes for the EWSR1- ATF1 fusion in clear cell sarcoma (CCS) requires further characterization. Here, the authors investigate the ... WebOct 1, 2014 · EWSR1 and ATF1 probes were successfully hybridized to the tumor sections and exhibited break-apart and fusion signals. Of the 200 tumor nuclei counted for each probe, more than 20% were found to exhibit rearrangement by showing separation of the 5′ and 3′ probes for both EWSR1 and ATF1 probes ( Figures 5 and 6 , respectively). black label society scars piano