Dimethyl 1 diazo 2 oxopropyl phosphonate
WebMar 3, 2024 · Reagents and conditions: (a) PyBOP, DIPEA, NaBH 4, THF, 1 h; (b) Dess-Martin periodinane, CH 2 Cl 2, 4 h; (c) dimethyl (1-diazo-2-oxopropyl)phosphonate, K 2 CO 3, MeOH, 0 °C, 2 h, rt, overnight; (d) ... 10 min; (f) dimethyl (1-diazo-2-oxopropyl)phosphonate, K 2 CO 3, MeOH, 0 °C, 4 h; (g) HCl (4 M)/MeOH (3:5), reflux, … WebDiethyl and dimethyl (1-diazo-2-oxopropyl)phosphonate 1 and 2 (Scheme 1) are versatile building blocks for organic synthesis. 2 These diazo compounds react via dipolar cycloaddition and other pathways to provide access to diverse classes of nitrogen heterocycles including phosphoryl-substituted pyrazoles, triazolines, oxazoles, and …
Dimethyl 1 diazo 2 oxopropyl phosphonate
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WebAbstract Dimethyl (1-diazo-2-oxopropyl) phosphonate (3) was transformed to dimethyl (diazomethyl)—phosphonate (4), which was used for the synthesis of enol ether or alkyne without isolation. View via Publisher Save to Library Create Alert Cite 503 Citations Citation Type More Filters WebMar 14, 2008 · Alternate Name: dimethy(1-diazo-2-oxopropyl) phosphonate. Solubility: H 2 O (no data); alcohols (MeOH); chloroalkanes (CHCl 3). Form Supplied in: colorless to yellow liquid; one supplier (Digital Specialty Chemicals Ltd.). Analysis of Reagent Purity: IR, NMR (CDCl 3). Purification: flash column chromatography (silica-gel, PE–EtOAc, 1:1).
WebThe dimethyl (diazomethyl)phosphonate carbanion can be generated in situ from dimethyl-1-diazo-2-oxopropylphosphonate (also called the Ohira-Bestmann reagent) by reaction with methanol and potassium carbonate as the base by cleavage of the acetyl group as methyl acetate. WebOct 23, 2006 · Dimethyl (1-diazo-2-oxopropyl) phosphonate (3) was transformed to dimethyl (diazomethyl)—phosphonate (4), which was used for the synthesis of enol …
WebDimethyl(1-diazo-2-oxopropyl)phospho-nate C5H9N2O4P CID 129710842 - structure, chemical names, physical and chemical properties, classification, patents, literature, … WebJun 17, 2002 · On the other hand, dimethyl 1-diazo-2-oxopropyl phosphonate 4 is easier to prepare 14 and alkyne formation (K 2 CO 3, rt, MeOH) 12 avoids the use of strong bases, low temperature and tolerates various functional groups. 15 Using diazophosphonate 3, we obtained alkyne 1a in 60% yield 1b while using 4 we and others obtained yields ranging …
WebJan 4, 2024 · Its name is Dimethyl (1-diazo-2-oxopropyl)phosphonate Chemsrc provides CAS#:90965-06-3 MSDS, density, melting point, boiling point, structure, etc. CAS Number Search
WebDimethyl (1-Diazo-2-oxopropyl)phosphonate 90965-06-3 TCI AMERICA Register today for easy order tracking, quick service, and free shipping on orders over $75! CAS RN: … how to eat canned kippersWebDimethyl (1-Diazo-2-oxopropyl)phosphonate. for Organic Synthesis. Specification Assay : 97.0+% (HPLC) Manufacturer : FUJIFILM Wako Pure Chemical Corporation. Storage … leda upp architectureWebDimethyl (1-Diazo-2-oxopropyl)phosphonate 90965-06-3 TCI AMERICA Register today for easy order tracking, quick service, and free shipping on orders over $75! CAS RN: … how to eat canned smoked musselsWebDimethyl (1-diazo-2-oxopropyl)phosphonate solution ~10% in acetonitrile (H-NMR), ≥96% (HPLC) Synonym (s): Bestmann-Ohira Reagent, Dimethyl (1 … leda\\u0027s boutique burrows road pinawa mbWebThe dimethyl (diazomethyl)phosphonate carbanion can be generated in situ from dimethyl-1-diazo-2-oxopropylphosphonate (also called the Ohira-Bestmann reagent) by … how to eat canned mackerel filletsWebLearn more about Dimethyl (1-diazo-2-oxopropyl)phosphonate. We enable science by offering product choice, services, process excellence and our people make it happen. how to eat can tunaWebDimethyl (diazomethyl)phosphonate C3H7N2O3P CID 5115033 - structure, chemical names, physical and chemical properties, classification, patents, literature ... how to eat cape gooseberry