WebVarious active anticancer agents are derived from plants and terrestrial microorganisms. The isolation of C-nucleosides from the Caribbean sponge, Cryptotheca crypta, four decades ago, provided the basis for the synthesis of cytarabine, the first marine-derived anticancer agent to be developed for clinical use. Cytarabine is currently used in the routine … WebApr 30, 2004 · Those drugs can be traced to nucleosidic compounds that chemist Werner Bergmann isolated from a Caribbean sponge, Cryptotheca crypta, in the 1950s. “These are arguably the first marine drugs,”...

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WebCryptotethya crypta, a sponge that yields very important medicinal derivatives, was originally found in the shallow waters off the coast of Elliot Key, Florida, in 1945 by a young scientist by the name of, Werner … WebSeveral molecules with biological activity were isolated, and most of them were typically obtained from corals, sponges, or other invertebrates. The first marine bioactive compounds, spongouridine and spongothymidine, were isolated from the … WebJan 1, 2007 · Marine invertebrate biodiversity also represents a vast resource of novel bioactive compounds, such as the anticancer agent developed from the Caribbean sponge Cryptotheca crypta (McConnell et al ... eros online shopping